Preseason
| September | Opponent | Location | Time (ET) | TV Network | |
| Tue Sep 21 | Devils | Philadelphia | 7:00 PM | TCN-PH | Tickets |
| Thu Sep 23 | Maple Leafs | London, On | 7:00 PM | Tickets | |
| Fri Sep 24 | @Maple Leafs | Toronto | 7:00 PM | Tickets | |
| Sat Sep 25 | @Wild | Minnesota | 8:00 PM | Tickets | |
| Tue Sep 28 | @Devils | New Jersey | 7:00 PM | Tickets | |
| Wed Sep 29 | Islanders | Philadelphia | 7:00 PM | TCN-PH | Tickets |
| October | Opponent | Location | Time (ET) | TV Network | |
| Fri Oct 1 | Sabres | Philadelphia | 7:00 PM | CSN-PH | Tickets |
| Sun Oct 3 | @Sabres | Buffalo | 6:00 PM | Tickets |
Regular Season
| October | Opponent | Location | Time (ET) | TV Network | |
| Thu Oct 7 | @Penguins | Pittsburgh | 7:00 PM | Versus | Tickets |
| Sat Oct 9 | @Blues | ST. Louis | 8:00 PM | Tickets | |
| Mon Oct 11 | Avalanche | Philadelphia | 7:00 PM | Tickets | |
| Thu Oct 14 | Lightning | Philadelphia | 7:00 PM | VERSUS, RIS | Tickets |
| Sat Oct 16 | Penguins | Philadelphia | 6:00 PM | Tickets | |
| Thu Oct 21 | Ducks | Philadelphia | 7:00 PM | Tickets | |
| Sat Oct 23 | Maple Leafs | Philadelphia | 7:00 PM | CBC | Tickets |
| Mon Oct 25 | @Blue Jackets | Columbus | 7:00 PM | Tickets | |
| Tue Oct 26 | Sabres | Philadelphia | 7:30 PM | VERSUS, TSN2 | Tickets |
| Fri Oct 29 | @Penguins | Pittsburgh | 7:00 PM | Tickets | |
| Sat Oct 30 | Islanders | Philadelphia | 7:00 PM | Tickets |
| November | Opponent | Location | Time (ET) | TV Network | |
| Mon Nov 1 | Hurricanes | Philadelphia | 7:00 PM | Tickets | |
| Thu Nov 4 | Rangers | Philadelphia | 7:00 PM | RIS | Tickets |
| Sat Nov 6 | @Islanders | New York | 7:00 PM | Tickets | |
| Sun Nov 7 | @Capitals | Washingon DC | 5:00 PM | RIS | Tickets |
| Thu Nov 11 | @Hurricanes | Carolina | 7:00 PM | Tickets | |
| Sat Nov 13 | Panthers | Philadelphia | 7:00 PM | Tickets | |
| Mon Nov 15 | Senators | Philadelphia | 7:00 PM | RDS | Tickets |
| Tue Nov 16 | @Canadiens | Montreal | 7:00 PM | RDS,VERSUS | Tickets |
| Thu Nov 18 | Lightning | Philadelphia | 7:00 PM | Tickets | |
| Sat Nov 20 | @Capitals | Washington DC | 7:00 PM | Tickets | |
| Mon Nov 22 | Canadiens | Philadelphia | 7:00 PM | RDS | Tickets |
| Wed Nov 24 | @Wild | Minnesota | 8:00 PM | Tickets | |
| Fri Nov 26 | Flames | Philadelphia | 1:00 PM | Tickets | |
| Sat Nov 27 | @Devils | New Jersey | 1:00 PM | Tickets |
| December | Opponent | Location | Time (ET) | TV Network | |
| Wed Dec 1 | Bruins | Philadelphia | 7:00 PM | Tickets | |
| Sat Dec 4 | Devils | Philadelphia | 1:00 PM | Tickets | |
| Sun Dec 5 | @Islanders | New York | 1:00 PM | NHLN-CA | Tickets |
| Wed Dec 8 | Sharks | Philadelphia | 7:00 PM | Versus | Tickets |
| Thu Dec 9 | @Maple Leafs | Toronto | 7:00 PM | TSN | Tickets |
| Sat Dec 11 | @Bruins | Boston | 7:00 PM | Tickets | |
| Tue Dec 14 | Penguins | Philadelphia | 7:00 PM | RDS, VERSUS, TSN2 | Tickets |
| Wed Dec 15 | @Canadiens | Montreal | 7:30 PM | RDS, TSN | Tickets |
| Sat Dec 18 | Rangers | Philadelphia | 1:00 PM | Tickets | |
| Mon Dec 20 | Panthers | Philadelphia | 7:00 PM | Tickets | |
| Tue Dec 28 | @Canucks | Vancouver | 10:00 PM | TSN | Tickets |
| Thu Dec 30 | @Kings | Los Angeles | 10:30 PM | Tickets | |
| Fri Dec 31 | @Ducks | Anahiem | 8:00 PM | Tickets |
| January | Opponent | Location | Time (ET) | TV Network | |
| Sun Jan 2 | @Red Wings | Detroit | 5:00 PM | NHLN-CA | Tickets |
| Thu Jan 6 | @Devils | New Jersey | 7:00 PM | Tickets | |
| Sat Jan 8 | Devils | Philadelphia | 1:00 PM | Tickets | |
| Tue Jan 11 | @Sabres | Buffalo | 7:30 PM | Versus, TSN2 | Tickets |
| Thu Jan 13 | @Bruins | Boston | 7:00 PM | RDS | Tickets |
| Fri Jan 14 | @Thrashers | Atlanta | 7:30 PM | Tickets | |
| Sun Jan 16 | @Rangers | New York | 7:00 PM | Tickets | |
| Tue Jan 18 | Capitals | Philadelphia | 7:00 PM | Tickets | |
| Thu Jan 20 | Senators | Philadelphia | 7:00 PM | RDS | Tickets |
| Sat Jan 22 | Devils | Philadelphia | 1:00 PM | Tickets | |
| Sun Jan 23 | @Blackhawks | Chicago | 4:00 PM | RDS,NHLN-CA,NBC | Tickets |
| Tue Jan 25 | Canadiens | Philadelphia | 7:30 PM | RDS,Versus | Tickets |
| February | Opponent | Location | Time (ET) | TV Network | |
| Tue Feb 1 | @Lightning | Tampa Bay | 7:30 PM | Tickets | |
| Thu Feb 3 | Predators | Philadelphia | 7:00 PM | RDS | Tickets |
| Sat Feb 5 | Stars | Philadelphia | 7:00 PM | RDS | Tickets |
| Thu Feb 10 | Hurricanes | Philadelphia | 7:00 PM | Tickets | |
| Sun Feb 13 | Kings | Philadelphia | 3:00 PM | NBC | Tickets |
| Tue Feb 15 | @Lightning | Tampa Bay | 7:30 PM | Tickets | |
| Wed Feb 16 | @Panthers | Florida | 7:30 PM | Tickets | |
| Fri Feb 18 | @Hurricanes | Carolina | 8:00 PM | Tickets | |
| Sun Feb 20 | @Rangers | New York | TBD | NBC | Tickets |
| Tue Feb 22 | Coyotes | Philadelphia | 7:00 PM | Tickets | |
| Thu Feb 24 | Islanders | Philadelphia | 7:00 PM | Tickets | |
| Sat Feb 26 | @Senators | Ottawa | 7:00 PM | CBC | Tickets |
| March | Opponent | Location | Time (ET) | TV Network | |
| Thu Mar 3 | Maple Leafs | Philadelphia | 7:00 PM | Tickets | |
| Sat Mar 5 | Sabres | Philadelphia | 1:00 PM | Tickets | |
| Sun Mar 6 | @Rangers | New York | 3:00 PM | NBC | Tickets |
| Tue Mar 8 | Oilers | Philadelphia | 7:00 PM | Tickets | |
| Thu Mar 10 | @Maple Leafs | Toronto | 7:00 PM | Tickets | |
| Sat Mar 12 | Thrashers | Philadelphia | 7:00 PM | Tickets | |
| Tue Mar 15 | @Panthers | Florida | 7:30 PM | Tickets | |
| Thu Mar 17 | @Thrashers | Atlanta | 7:00 PM | Tickets | |
| Sat Mar 19 | @Stars | Dallas | 8:00 PM | Tickets | |
| Tue Mar 22 | Capitals | Philadelphia | 7:30 PM | Versus,TSN2 | Tickets |
| Thu Mar 24 | Penguins | Philadelphia | 7:00 PM | Tickets | |
| Sat Mar 26 | @Islanders | New York | 7:00 PM | Tickets | |
| Sun Mar 27 | Bruins | Philadelphia | 7:00 PM | RDS | Tickets |
| Tue Mar 29 | @Penguins | Pittsburgh | 7:00 PM | Tickets | |
| Thu Mar 31 | Thrashers | Philadelphia | 7:00 PM | Tickets |
| April | Opponent | Location | Time (ET) | TV Network | |
| Fri Apr 1 | @Devils | New Jersey | 7:00 PM | RIS | Tickets |
| Sun Apr 3 | Rangers | Philadelphia | 3:00 PM | NHLN-CA,NBC | Tickets |
| Tue Apr 5 | @Senators | Ottawa | 7:30 PM | Tickets | |
| Fri Apr 8 | @Sabres | Buffalo | 7:30 PM | Tickets | |
| Sat Apr 9 | Islanders | Philadelphia | 7:00 PM | Tickets |